phospholipase c-epsilon pathway
| PAG Title | phospholipase c-epsilon pathway |
| PAG ID | WAG000849 |
| Type | P |
| Source Link |  BioCarta |
| Publication Reference | NA |
| PAG Description | Proposed model for b2-AR- and prostanoid-receptor-mediated PLC and calcium siglling. Receptors coupling to Gs stimulate AC, resulting in elevated cAMP levels and activation of Epac1. Epac1 then catalyses GTP-loading on Rap2B, which leads to PLC-e activation. The proposed pathway may involve additiol siglling components to attain PLC stimulation. |
| Species | Homo sapiens |
| nCoCo Score | 1,044 |
| Base PAG ID | WAG000849 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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